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The ACMS intermediate can be metabolized via the action of the enzyme ACMS decarboxylase encoded by the ACSMD gene

If two compounds a and b produce a specified effect that can each be independently parameterized by a four parameter Hill equation (Eq

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Chondrocyte dedifferentiation was majorly characterized as the reduced expression of COL2 and ACAN and enhanced expression of type I collagen and versican ( COL2 expression, but not ACAN ( In addition to dedifferentiation, another consequence of in vitro expansion is replicative senescence, which also significantly influences chondrocyte function