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Aunque estudios en roedores mostraron asociacin con tumores de clulas C tiroideas, esta relacin no se ha confirmado definitivamente en humanos

Mechanism of Action When GLP-1 peptides are administered, they bind to the GLP-1 receptors in the brain, pancreas, and gastrointestinal tract, leading to several key effects: Increased Insulin Secretion: Enhances insulin release in response to meals

If scheduled for surgery or procedures requiring anesthesia, patients should discuss their medication with both their prescriber and surgical team, as delayed gastric emptying may affect anesthesia planning

We urge anyone who has concerns about this medication to speak to their pharmacist for advice. In January 2025, the MHRA warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using GLP-1 RAs who undergo surgery or procedures with general anaesthesia or deep sedation