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Cagrilintide is engineered around that problem: it is a modified, lipidated peptide that acts as a dual amylin and calcitonin receptor agonist and is stable enough for once-weekly subcutaneous dosing

Dependency on Maintenance Doses: Continuous maintenance may be required to preserve the whitening effect, adding to long-term costs

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7.2 Integration of multi-omics approaches We proposed that future research should combine metagenomics, metabolomics, and transcriptomics to better elucidate the complex interactions between gut microbiota alterations and hepatic metabolic dysfunction in cadmium-induced liver injury