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In summary, in metformin-treated patients with well-controlled type 2 diabetes, metformin is more effective in glucose-lowering when given before, rather than with, enteral glucose, and this is associated with a greater GLP-1 response

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This change, implemented in 2023, aligns Ozempics label with those of related GLP-1 drugs like Wegovy and Mounjaro, which had previously listed this risk