glp-1 news today november 5 2025 Drugs: Pulse Survey (U.S.) GLP-1: Transforming weight loss and

Acute gallbladder disease In trials for Mounjaro, 0.6% of participants reported gallbladder disease including gallstones, gallbladder inflammation, biliary colic (intermittent or constant abdominal pain), and cholecystectomy (surgical removal of the gallbladder)compared to 0% in the placebo group

Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks

10.1074/jbc.m109.032888 J

If NSAIDs arent suitable for you, paracetamol is an alternative but less effective for menstrual pain