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Key principles often include: Holding weight stable before dose reductions Avoiding simultaneous aggressive calorie restriction Maintaining protein intake and resistance training Supporting metabolic health during transition The goal is not continued weight loss during tapering it is durable stability

This is sometimes referred to as functional hypothalamic amenorrhoea, which can occur with rapid weight loss or significant energy deficits

Combining Semaglutide with Lifestyle Changes Semaglutide is powerful, but it isnt a magic solution on its own

Side Effects and Tolerability The most common side effects are gastrointestinal: Nausea: Affects 20-40% of patients, usually most prominent during dose increases and improving over weeks