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reported that Shaoyao-Gancao Decoction (SGD), commonly used to treat multiple gynecological disorders such as dysmenorrhea, adenomyosis, and PCOS, modulated gut microbiota composition, and alleviated chronic low-grade inflammation by downregulating cytokines including IL-18, IL-1, IL-6, and TNF- in both serum and ovarian mRNA expression in PCOS rats (238)

doi: 10.3389/fmicb.2024.1328324 46 GracieDJHamlinPJFordAC

BPC-157 also has anti-inflammatory properties, helping to reduce pain and swelling

These saponin components act through multiple targets and pathways, including anti-oxidative stress, anti-inflammatory, and anti-apoptotic mechanisms