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Abdelrazik H, Sharma R, Mahfouz R, Agarwal A

Other pharmaceutical companies may be assessing the impact on their portfolio and reviewing their current R&D pipeline and priorities

If you've completed 8 weeks and notice minimal weight change, several factors may apply: medications that interfere with GLP-1 signaling, thyroid dysfunction, insulin resistance patterns, or genetic variants that require a higher dose threshold

It is also important to consider that many patients prescribed tirzepatide are concurrently taking other medications that can affect blood pressure, such as antihypertensives, diuretics, or SGLT2 inhibitors , which may compound the risk of postural hypotension