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A role for GLP-1 in regulating glycaemia had been noted in 1986, when this, then newly described (8, 9), peptide was found to have profound effects upon the endocrine pancreas

Protein-bound uremic toxins (IS, pCS, PAGln) accumulate exponentially as eGFR declines below 60 mL/min/1.73 m 2 due to saturable OAT1/3-mediated tubular secretion (113, 167), with patients at eGFR 30 exhibiting 510 higher IS than those at eGFR 90reflecting clearance impairment rather than unique pathogenic mechanisms

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Jego rola w utrzymaniu zdrowia mzgu sprawia, e jest szczeglnie istotny w kontekcie osb, ktre chc wspiera swoj pami, koncentracj i sprawno umysow