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The parallel: GLP-1 proved in diabetes expanded to obesity then everything Orexin is proving in narcolepsy expanding to ADHD, chronic fatigue, AD The players: Alkermes alixorexton (Phase 3, T2 narcolepsy) Takeda danavorexton (Phase 3, T1 narcolepsy) Eisai E2027 (Phase 2) Lilly Centessa others undisclosed programs Why this matters: Orexin regulates reward, attention, motivation, and energy metabolism

By binding to GLP-1 receptors in multiple tissues, Ozempic influences several physiological processes that affect glucose regulation and appetite control

What Is GLP-1 and Why It Matters After Pregnancy GLP-1 (Glucagon-Like Peptide-1) is a hormone released in your gut after you eat