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Distilled off the solvent from the organic layer under reduced pressure and co-distilled with n-heptane

This occurs because semaglutide slows gastric emptying as part of its mechanism of action, which can lead to harder, less frequent stools

Speak to your GP if you experience: Severe or persistent abdominal pain, particularly in the upper right or upper middle abdomen Jaundice (yellowing of the skin or whites of the eyes) Persistent vomiting Dark urine or pale stools Fever alongside abdominal symptoms Persistent watery or urgent diarrhoea that doesnt settle after the first few weeks on a stable Mounjaro dose Heartburn or reflux is noticeably worse than before starting Mounjaro Some people experience increased bile reflux after gallbladder removal, and Mounjaros slowing of gastric emptying can make this worse

The gradual escalation minimises GI side effects