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( + ions, which altered pH, and the alteration of the pH led to an increase in melanin production by correcting the trafficking of tyrosinase, the enzyme that catalyzes the rate-limiting step of melanogenesis, and tyrosine-related protein-1 (TRP-1) to the proper compartments ( Figure 2A )
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The most commonly reported effects include injection site reactions (redness, mild swelling, itching), joint pain or stiffness, numbness or tingling in the extremities (paresthesia), headaches, and mild fluid retention
CNS remyelination and inflammation: from basic mechanisms to therapeutic opportunities
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