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Food and Drug Administration-approved (FDA-approved) for the treatment of type 2 diabetes and has an additional indication for reducing the risk of major cardiovascular events, such as heart attack or stroke in individuals with type 2 diabetes and cardiovascular disease

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Analysts had prior to the results called the trial a long shot, whereas Novo itself had referred to it as a "lottery ticket." "Based on the significant unmet need in Alzheimer's disease as well as a number of indicative data points, we felt we had a responsibility to explore semaglutide's potential, despite a low likelihood of success," said Novo's chief scientific officer, Martin Holst Lange

Histological verification of cannula placement was accomplished by the injection of 5 fast-green dye via the guide cannula following the completion of behavioral testing