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Berberine has a short half-life, so divided dosing throughout the day is commonly used in studies to maintain more stable blood levels

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This solid state is preferred for shipping and long-term storage because it maximizes stability and extends the shelf life of the delicate peptide molecules [1]

The therapy counteracted both early and delayed neural hippocampal damage, achieving full functional recovery (Morris water maze test, inclined beam-walking test, lateral push test) [38], as assessed at 24 h and 72 h of the reperfusion