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Spotting B12 Deficiency The Hidden Fatigue Causes & Vitamin Deficiency Symptoms Common fatigue causes related to B12 deficiency In cases where you are incessantly fatigued and sleep adequately , the following are the B12-linked reasons: Malabsorption: You may be consuming vitamin-rich foods that contain B12, but it does not work because you have low stomach acid levels, your stomach has been operated on or you are taking medicines such as PPIs or metformin

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doi: 10.1016/S1474-4422(13)70044-9