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[DOI] [PMC free article] [PubMed] [Google Scholar] [83].Montero D, Walther G, Stehouwer CD, Houben AJ, Beckman JA, Vinet A, Effect of antioxidant vitamin supplementation on endothelial function in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

Most patients notice improvements within 23 weeks, with results continuing to improve over time