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The study used a randomized, double-blind, placebo-controlled, crossover-designed trial and concluded, oral nicotinamide riboside increased human skeletal muscle NAAD, a sensitive marker of increased NAD+ metabolism. Seventh Human Niagen Study That Demonstrates Effectiveness: A study published in The American Journal of Clinical Nutrition in 2020 investigated the effects of Niagen on metabolic health, muscle metabolism, and mitochondrial function

doi: 10.1126/science.ads0018 133 HeF.WuH.ZhouL.LinQ.ChengY.SunY

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