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An exploratory analysis of genetic data of patients from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial showed that different haplotypes encoding for GLP-1R correlated with variable response rates to antipsychotic medications 132
That would be too broad
The SELECT trial further showed that once-weekly semaglutide reduced first-event MACE by 20% in adults with obesity and prior cerebrovascular disease, extending cardiovascular protection beyond diabetes [319, 320]
New oral formulations, including Wegovy in pill form and Eli Lilly's Foundayo, may broaden access and accelerate research into lower-dose and weight-maintenance strategies
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