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In the Phase 2 trial, participants showed reductions in liver fat content as measured by MRI-based proton density fat fraction (MRI-PDFF) assessments, with some individuals demonstrating marked reductions in hepatic steatosis

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How Much Weight Loss Do Clinical Trials Show: Retatrutide vs Tirzepatide Weight Management Research Data Phase 3 clinical trial data places retatrutides average body weight reduction at approximately 28% over 18 months, a figure that Eli Lilly and independent commentators have described as comparable to outcomes typically associated with bariatric surgery [2]