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Effect of linagliptin vs placebo on major cardiovascular events in adults with type 2 diabetes and high cardiovascular and renal risk: the CARMELINA randomized clinical trial

These cellular stressors activate inflammatory cascades involving Kupffer cells, recruited macrophages, and other immune cells, perpetuating hepatic inflammation through secretion of inflammatory mediators and cellular damage signals [7]

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Laboratory interest includes its interaction with lipolysis-associated signaling, metabolic regulation pathways, and energy balance mechanisms