Potential Risks or Downsides of NAD+ Anti-Aging Injections Even though NAD+ is natural, injections still carry potential risks, including: Nausea, flushing, chest or abdominal discomfort during IV infusion Headaches or fatigue afterward Pain, bruising, or infection at injection sites Phlebitis (vein inflammation) Allergic reactions to components of the infusion Unknown long-term safety, especially with repeated high doses There are also theoretical concerns for individuals with a history of cancer because NAD+ pathways play a role in cell growth and repair
Several studies have shown that TGF-1 upregulates glutaminase 1 (GLS1), enhancing the conversion of glutamine to glutamate, a critical step for collagen biosynthesis [97,98,99]
Circadian control of antigen-specific T cell responses
In rare cases, an MRI scan of the neck is arranged, to investigate if the problem is coming from the neck