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Insulin resistance was assessed using the homeostasis model assessment of insulin resistance (HOMA-IR)

Pre-clinical research has shown that gingerol potentiates GLP-1 activity , and facilitates glucose uptake in skeletal muscles through increased activity of glycogen synthase 1 and enhanced cell surface presentation of GLUT4 transporters, 16,17 proteins that play a central role in regulating blood glucose levels by facilitating the transport of glucose across the cell membrane

Experts also have concerns that the drug needs to be given alongside the support provided by specialist weight management services for the treatment to work

The most commonly available probiotics are called Lactobacilli and Bifidobacteria