Patch pipettes (47 M resistance, Warner Instruments, MA, USA) were prepared using a micropipette puller (PC-100, Narishige, Japan) and filled with an internal solution containing: 135 mM CsCl, 4 mM NaCl, 0.5 mM CaCl 2 , 10 mM HEPES, 5 mM EGTA, 2 mM MgATP, 0.5 mM Na 2 GTP, 10 mM QX-314, and adjusted to pH 7.2 with CsOH, 278285 mOsmol
Strength and Conditioning Journal, 36 (2), 45-48
Summary: GLP-1 medications are associated with a small increased risk of diabetic retinopathy progression in some patients, but complete vision loss is rare and most eye complications are manageable with early detection
Most lyophilized peptides occupy a negligible volume once dissolved, but some formulations include bulking agents that add measurable volume