Curcumin reduces the hepatotoxicity induced by arsenic, cadmium, chromium, copper, lead, and mercury, prevents histological injury, lipid peroxidation, and glutathione (GSH) depletion, maintains the liver antioxidant enzyme status and protects against mitochondrial dysfunction. Curcumin shows tumor inhibiting activity in thyroid cancer
Richter A, Seidl-Adams I, Kllner TG et al (2015) A small, differentially regulated family of farnesyl diphosphate synthases in maize ( Zea mays ) provides farnesyl diphosphate for the biosynthesis of herbivore-induced sesquiterpenes
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The pivotal role of cysteine (the reduced form of cystine) as the rate-limiting substrate for GSH synthesis becomes evident here