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International Journal of Dermatology , 60 (8), 1013-1018

This re-conceptualization of oxidative stress as a disruption of redox signaling and control may explain why some of the previously conducted antioxidant supplementation trials focused solely on the mitigation of global oxidant/antioxidant imbalance have failed to yield significant results

193 There is also evidence that physical activity and nutrition have preventive effects and metabolic improvement independent of body weight

171,172,173,174 Evidence suggests that molecules present in platelets, such as HGF, serotonin, platelet-derived growth factor (PDGF), VEGF and insulin-like growth factor (IGF), are involved in directly mediating hepatocyte proliferation