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On average, people lost around 15 to 21% of their starting body weight , with the biggest changes showing up after staying on the medication long enough for doses to increase and stabilize

It was interesting that 13 samples showed a direct correlation for GLP-1R expression between the primary site and its metastatic counterpart, while the remaining two samples with negative GLP-1R expression in the primary site showed positive GLP-1R expression in the metastatic site, suggesting that cells expressing GLP-1R may have an increased metastatic ability

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