The current study also addressed ED by PDU, a second-level diagnostic tool with respect to ED diagnosis, by providing further objective information concerning the penile erectile function, and particularly the vascular status, compared to clinical information deriving from first-level diagnostic tools, such as anamnesis and standardized questionnaires [32,33,34]
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Furthermore, advancements in delivery systems, such as nanotechnology-based formulations, offer promising solutions to enhance bioavailability while minimizing toxicity