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UnitedHealth Group is the market leader, and between 2024 and 2025 it achieved the largest absolute enrollment gain (adding roughly 505,000 MA members)

The popularity of GLP-1 medications has led to a wave of products marketed as a natural GLP-1 supplement. These are usually patches, drops, fibre supplements, and herbal formulations promising similar effects without a prescription

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[5] Several biological mechanisms have been proposed in preclinical research that suggest plausible links between GLP-1 signalling and brain health: Neuroprotection : In laboratory and animal studies, GLP-1 receptor activation may protect neurons from oxidative stress and inflammation, both of which contribute to neurodegeneration [5] Neurogenesis : Animal studies suggest GLP-1 may promote the growth of new neurons in the hippocampus, a region essential for memory Reduction of amyloid plaques : Preclinical research indicates potential effects on beta-amyloid accumulation, a hallmark of Alzheimer's disease [5] Anti-inflammatory effects : Chronic neuroinflammation is implicated in various forms of dementia The connection between metabolic health and cognitive function provides additional rationale for investigating GLP-1 agents in dementia