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GLP-1s provide guardrails for patients by reducing their desire, lowering their threshold for nausea, forcing them to drink at a slower pace and exacerbating the hangover, thereby creating a negative feedback loop in which the patient can continue to drink but simply doesnt do so excessively, le Roux said

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Individuals should also discuss any supplements or experimental compounds they are considering with their healthcare provider, particularly if they have chronic medical conditions, are pregnant or breastfeeding, or take prescription medications

The effects run almost equally in both directions which tells you this is not a simple story