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224 The decrease in GSH and GPX4 leads to increased tissue damage in animal models of ferroptosis and diabetes

2018, doi:10.3390/molecules23030575 Derosa, Giuseppe et al

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Ongoing studies on KL1s mechanism, along with medicinal chemistry optimization and in vivo testing in combination with diverse antibiotics against multiple pathogens, will be critical to determine the full therapeutic potential of this host-directed adjuvant in eradicating deep-seated infections