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In standard microneedling protocols, these channels are the mechanism through which the wound healing cascade is activated

In the CPZ model, researchers gave mice NLY01 at the beginning of CPZ induction

10.3109/13685538.2014.888053 Pubmed Abstract CrossRef Google Scholar View reference in article 44

So for the most common long-term situation, an absorption problem, maintenance means one injection every two to three months rather than anything weekly or monthly