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During a median follow-up of 5.4 (IQR 5.15.9) years, patients with a 1.5 mg/week subcutaneous injection of dulaglutide showed a lower incidence rate of the primary composite outcome including non-fatal myocardial infarction, non-fatal stroke, or death from cardiovascular causes ( HR = 0.88, 95% CI 0.790.99, P = 0.026) [62]

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Given that GLP-1RAs exert beneficial effects on risk factors for new-onset AF (e.g., body weight, blood pressure, renal function, and glycemic control), their impact on AF events has emerged as an area of growing interest in academia and clinical settings (118, 119)

However, the authors note that the study was limited in that it could not prove cause and effect