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Similar content being viewed by others 1 Introduction Diabetes mellitus (DM) is a metabolic condition characterized by high blood sugar levels due to insufficient insulin production or reduced insulin effectiveness

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For example, studies have explored how ACSL4 inhibitors can improve organ ischemia-reperfusion injury and how LPCAT3 inhibitors can reshape the polyunsaturated phospholipid content of human cells to prevent ferroptosis (31, 32)