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The study medication was stored in a study refrigerator and protected from light until 30 min before administration, when it was allowed to come to room temperature, for participant comfort during administration

In the promoter of both gliM and gliT there is a ZR-like motif located respectively at 124 and 483 bp upstream of the TSC, whereas in the gliA promoter there are two ZR-like motifs located at 455 and 508 bp upstream of its TSC (Vicentefranqueira et al., 2018)

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