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Research suggests that SIBO is involved in up to 78% of irritable bowel syndrome (IBS) cases, the most commonly diagnosed disorder of gastrointestinal motility (170)

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A 54% reduction in their ability to clump together is substantial, comparable to the effect of low-dose aspirin

In the model proposed by Lee, homocysteine is shunted away from the methionine synthesis pathway and toward the GSH synthesis pathway, creating a relative deficiency of methyl donors in order to keep up with increased demand for the glutathione needed for POP conjugation ( Fig 3 )