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These findings warrants future investigation as to whether exenatide protects cognition via reduction of ICP or other neuroprotective mechanisms

Depending on the specific medication prescribed, injections may be required once daily or just once weekly

If side effects are severe or persistent beyond the first few weeks, your GP or diabetes specialist may suggest: Temporary dose reduction Anti-emetic medication for nausea Review of concomitant diabetes medications to reduce hypoglycaemia risk Alternative GLP-1 receptor agonist formulations if oral semaglutide remains poorly tolerated According to NICE guidelines (NG28) , treatment decisions should be individualised based on efficacy, tolerability, patient preference, and cost-effectiveness