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Diabetes medications: GLP-1 agonists and GH secretagogues affect glucose

Simultaneous pharmacological targeting of receptors enriched in the gut and pancreas, which have dual functions in the release of anorectic peptides from EECs and incretin effects, might be beneficial in diabetic obese patients

Although the FDA has issued a boxed warning for semaglutide, based on animal studies indicating a risk for thyroid C-cell tumors [48], no target-organ toxicity emerged, and there was no signal for thyroid C-cell hyperplasia, an observation later corroborated in clinical trials

Cholesterol in islet dysfunction and type 2 diabetes