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Improved Detoxification Supports liver health and efficient toxin elimination

Glutaminase is actively expressed in periportal liver cells, renal epithelial cells, and the central nervous system, which is used to synthesize urea and neurotransmitters

In accordance with this, it has been estimated that the steady-state concentration of superoxide in the mitochondrial matrix is 5- to 10- fold higher than in the cytosol (Fernandez-Checa and Kaplowitz, 2005

In the context of inflammatory skin diseases, oxidative stress can disrupt the skin's hydrolipid barrier, damage keratinocyte DNA, oxidize lipids in the stratum corneum, and induce the production of pro-inflammatory cytokinesinterleukin-1 (IL-1) and interleukin 33 (IL-33)in the dermis, promoting inflammation and exacerbating the disease (120)