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The root and leaves of ashwagandha contain bioactive compounds, most notably steroidal lactones called withanolides, which have shown broad biologic activity in laboratory and animal studies

Emerging evidence demonstrates that miRNAs are critical regulators of lipid synthesis and FAO 81 resulting in defective cell metabolism and carcinogenesis 82 directly targeting key enzymes or transcription factors as oncogenes and tumor suppressors 81 as shown in Table 1

However, because dietary groups differed prior to intervention, the study cannot fully disentangle prebiotic effects from those attributable to the pre-existing diet

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