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Compared to BPH specimens, malignant prostate tissue has relatively low levels of selenium [89]

Cells were mixed with 2 g of GFP-LC3B (Beyotime Biotechnology) and 100 nM Mito-Tracker Red CMXRos, then treated with the indicated concentrations of PTX to detect mitochondrial and autophagosome co-localization

By binding directly to IGF-1 receptors on muscle cells, IGF-1 LR3 activates downstream anabolic pathways including PI3K/Akt and MAPK signalingpromoting protein synthesis, glucose uptake, cellular proliferation, and satellite cell activation