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Because millions of people are already taking GLP-1s for health conditions like diabetes, obesity, and cardiovascular disease, with more indications in progress, there are millions of people who will reduce their substance use simply as an unexpected, and maybe even unnoticed, side effect of the medications, as well as millions more who will avoid developing addictions or unhealthy substance use patterns in the first place

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Prog Biophys Mol Biol 141:4759