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Measurement details Subjective feeling rating Participants were asked to rate their feeling of intoxication on a scale of 010, with 0 rated as not being drunk at all and 10 as the most drunk they have ever felt, by asking How drunk do you feel right now? Appetite score Participants were asked to indicate their current appetite using visual analog scales (VAS) as described by Flint and colleagues 78

GCGR antibody antagonist+LY 10 nmol/kg), n = 6

We evaluate at the end of each cycle before deciding whether to repeat, adjust the dose, add a stack partner like TB-500, or transition to a maintenance approach

The Journal of clinical investigation 2024;134