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The medication is administered once weekly via subcutaneous injection, typically starting at 2.5 mg and gradually increasing by 2.5 mg every 4 weeks up to a maximum of 15 mg, to minimise gastrointestinal side effects

In case of mortality within 5 postoperative days, patients were defined as PHLF when bilirubin and prothrombin time were altered according to the forementioned classification