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This doesn't mean these drugs aren't valuable, but it does support the NHS approach of prioritising people with severe and complex obesity who are most likely to benefit.' An estimated nine in ten people currently using weight-loss medicines in the UK are purchasing them privately, often without the comprehensive clinical oversight and behavioural support that accompanies NHS prescribing

GLP-1 Signaling at the Intersection of Metabolism and Reward The gut and brain communicate via the vagus nerve, so gut health directly impacts mood, anxiety, and neurodegenerative conditions

With consistent evidence for both glucose lowering and weight loss, these agents are sure to remain popular as long as they are accessible.

Blood glucose monitoring becomes particularly important during this period, and your healthcare team may need to adjust other diabetes medications to maintain control