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Administration Rules The injection can be taken at any time of day, with or without food, and requires refrigerated storage

[1] Unlike amphetamine abuse, where drug tolerance necessitates escalating doses to achieve the same effect, tolerance to clinically relevant doses of amphetamine plateaus after the initial titration period, and "drug holidays" (i.e., temporary treatment discontinuation) are not required to prevent the development of tolerance

A recent study found that the overall 12-month discontinuation rate of GLP-1 agonists was 36.5%

Since tissue repair occurs predominantly during these deep sleep stages, improved rest directly translates to accelerated recovery outcomes