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Proc Natl Acad Sci U S A , 110 (52), 2100621011

PLGA is a hydrophobic polymer, which is more suited to encapsulate hydrophobic rather than hydrophilic agents via two general methods 4 : (1) Nanoprecipitation, in which PLGA and agents to be encapsulated are dissolved in a good solvent and then co-precipitate into nanoparticles upon addition into a non-solvent for both

Circulation 2024;150:1781-90.ArticlePubMed 120