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Brutons tyrosine kinase and B-cell lymphoma-2 inhibitors are widely used in the clinic for the treatment of CLL

Colesevelam, which requires a much lower quantity of drug because of its high affinity and binding capacity for bile salts, has less of an effect on the absorption of other drugs than other bile acid sequestrants but can still adversely affect the absorption of certain drugs (Table 30) (424)

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