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From a practical standpoint, GHK-Cus tripeptide-copper complex is water-soluble and can be formulated in aqueous serums, while Matrixyls palmitic acid chain gives it a more lipophilic character suited to cream-based formulations

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For example, cellular senescence, classified as an antagonistic/secondary hallmark of aging, results as a consequence of persistent DNA and/or proteomic damage (primary hallmarks) that drives integrative hallmarks such as chronic inflammation and altered intracellular signaling, which further perpetuate other aging hallmarks

Modulates expression of over 4,000 genes involved in tissue remodeling, including upregulation of collagen, elastin, and glycosaminoglycan synthesis