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[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway

Rad AH, Abbasalizadeh S, Vazifekhah S, Abbasalizadeh F, Hassanalilou T, Bastani P, et al

Partnering with Acino strengthens distribution reach across South Africa and aligns with Novos broader strategy of tailoring GLP1 commercialization to emerging markets

Strong prescription momentum and expanding access build a solid fundamental outlook for these companies