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[16] [121] Upon leaving the stomach the hydrochloric acid of the chyme is neutralized in the duodenum by bicarbonate, [122] and pancreatic proteases release the vitamin from HC, making it available to be bound by IF, which is a protein secreted by gastric parietal cells in response to the presence of food in the stomach

Beyond serving as a reducing cofactor for antioxidant enzymes, GSH exerts direct antioxidant activity by scavenging reactive oxygen species (ROS) and RNS, including superoxide anions (O 2 ), H 2 O 2 , and hydroxyl radicals (OH) 3

They vary by manufacturer, dose, how they are taken and approved use